博安生物 BA1302在美国获准展开临床实验 06955.HK (博安生物BA1302)

【财华社讯】博安生物(06955.HK)发布，公司自主开发的靶向CD228创新抗体偶联药物(“ADC”)BA1302已取得美国食品药品监视控制局(“FDA”)容许展开临床实验。BA1302拟用于治疗多种实体瘤，此前已取得FDA授予的鳞状非小细胞肺癌和胰腺癌的孤儿药资历认定，正在中国启动1期临床研讨，全球进度抢先其他同类研发。

#include<reg52.h>#include<intrins.h>#include<math.h>#define uchar unsigned char#define uint unsigned int#define rst573 P2&=0X1F#define y4 P2|=0X80#define y5 P2|=0XA0#define y6 P2|=0XC0#define y7 P2|=0XE0sbit s5=P3^2;sbit s4=P3^3;sbit s6=P3^1;sbit s7=P3^0;sbit scl=P1^7;sbit IO=P2^3;sbit rst1302=P1^3;uchar code tab[]={0xc0,0xf9,0xa4,0xb0,0x99,0x92,0x82,0xf8,0x80,0x90};uchar code chu[]={0x01,0x02,0x04,0x08,0x10,0x20,0x40,0x80};uchar time[8]={0xa4,0xb0,0xbf,0x90,0x90,0xbf,0xc0,0xc0};uchar miao1,miao2,fen1,fen2,shi1,shi2,shi,fen;void delay(uint z){uint i,j;for(i=z;i>0;i--)for(j=120;j>0;j--);}void writebyte(uchar add,uchar date){uchar i;scl=0;IO=0;rst1302=1;for(i=0;i<8;i++){scl=0;IO=add&0x01;scl=1;add>>=1;}for(i=0;i<8;i++){scl=0;IO=date&0x01;scl=1;date>>=1;}rst1302=0;}uchar readbyte(uchar add){uchar i,temp;scl=0;IO=0;rst1302=1;for(i=0;i<8;i++){scl=0;IO=add&0x01;scl=1;add>>=1;}for(i=0;i<8;i++){scl=1;temp>>=1;scl=0;if(IO)temp|=0x80;}return temp;}void set1302(){writebyte(0x8e,0x00);writebyte(0x84,0x00);writebyte(0x82,0x00);writebyte(0x80,0x00);writebyte(0x8e,0x80);}void read1302(uchar *p){p[0]=readbyte(0x85);writebyte(0x84,0x00);p[1]=readbyte(0x83);writebyte(0x82,0x00);p[2]=readbyte(0x81);writebyte(0x00,0x00);}void zhuanghuan(){shi=time[0];fen=time[1];miao1=(time[2]/16)%10;miao2=(time[2]%16)%10;}void display(){rst573;P0=chu[0];y6;rst573;P0=tab[shi>>4];y7;delay(2);rst573;P0=chu[1];y6;rst573;P0=tab[shi&0x0f];y7;delay(2);rst573;P0=chu[3];y6;rst573;P0=tab[fen>>4];y7;delay(2);rst573;rst573;P0=chu[4];y6;rst573;P0=tab[fen&0x0f];y7;delay(2);rst573;P0=chu[6];y6;rst573;P0=tab[miao1];y7;delay(2);rst573;P0=chu[7];y6;rst573;P0=tab[miao2];y7;delay(2);rst573;P0=chu[2];y6;rst573;P0=0xbf;y7;delay(2);rst573;P0=chu[5];y6;rst573;P0=0xbf;y7;rst573;delay(1);read1302(time);zhuanghuan();}void jian(){if(s4==0){delay(5);if(s4==0){while(!s4)display();writebyte(0x8e,0x00);shi++;if(shi==10)//对应BCD的e799bee5baa6e997aee7ad94ee69d~9shi=16;if(shi==26)//对应BCD的10~19shi=32;if(shi==36)//对应BCD的19~23shi=0;writebyte(0x84,shi);}}if(s5==0){delay(5);if(s5==0){while(!s5)display();writebyte(0x8e,0x00);shi--;if(shi==-1) //对应BCD的23~20shi=35;if(shi==31) //对应BCD的19~10shi=25;if(shi==15) //对应BCD的9~0shi=9;writebyte(0x84,shi);}}if(s6==0){delay(5);if(s6==0){while(!s6)display();writebyte(0x8e,0x00);fen++;if(fen==10) //对应BCD的0~9fen=16;if(fen==26) //对应BCD的10~19fen=32;if(fen==42) //对应BCD的20~29fen=48;if(fen==58) //对应BCD的30~39fen=64;if(fen==74) //对应BCD的40~49fen=80;if(fen==90) //对应BCD的50~59fen=0;writebyte(0x82,fen);}}if(s7==0){delay(5);if(s7==0){while(!s7)display();writebyte(0x8e,0x00);fen--;if(fen==-1) //对应BCD的59~50fen=89;if(fen==79) //对应BCD的49~40fen=73;if(fen==63) //对应BCD的39~30fen=57;if(fen==47) //对应BCD的29~20fen=41;if(fen==31) //对应BCD的19~10fen=25;if(fen==15) //对应BCD的9~0fen=9;writebyte(0x82,fen);}}}void main(){set1302();while(1){jian();display();}}